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KMID : 0191119990140040448
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Journal of Korean Medical Science
1999 Volume.14 No. 4 p.448 ~ p.450
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Myelodysplastic syndrome that progressed to acute myelomonocytic leukemia with eosinophilia showing peculiar chromosomal abnormality: a case report
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Kim SH
Suh C/Choi SJ/Kim JG/Lee JH/Kim SB/Kim SW/Lee KH/Lee JS/Kim WK/Kim SH/Seo EJ/Chi HS
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Abstract
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Myelodysplastic syndrome is a closely related group of acquired bone marrow disorders characterized by ineffective and dysplastic hematopoiesis. These clonal disorders frequently progress to acute leukemia. Acute myelomonocytic leukemia with eosinophilia is characterized by an increase in abnormal eosinophils in the bone marrow, relatively good clinical course and inv (16) chromosomal abnormality. We experienced one case of refractory anemia with excess blasts which progressed to refractory anemia with excess blasts in transformation and finally to acute myelomonocytic leukemia with eosinophilia showing peculiar chromosomal abnormalities of der (1;7).
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KEYWORD
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Myelodysplastic syndromes, Leukemia, myelomonocytic, acute, Eosinophilia, Chromosome abnormalities
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